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Exterior of a modern industrial building with clean white panels, steps leading to an entrance, and silhouetted figures in front.

Advanced Manufacturing Facility.

At a glance

UK’s largest medicines development and manufacturing site.

Client

AstraZeneca

Highlights

  • Global cancer treatment preparedness programme
  • Supporting patients worldwide

A new advanced manufacturing facility to enable AstraZeneca to meet demand for their oncology medicine, Zoladex. The facility is part of a £380m manufacturing and packaging portfolio on AstraZeneca’s Macclesfield campus.

The complex sterile production process for the Zoladex drug relies solely on the manufacturing capabilities and skilled workforce of the campus, which is the UK’s largest medicines development and manufacturing site.

BakerHicks provided multi-disciplinary design services, including process engineering, architecture, civil and structural engineering, mechanical and electrical services, and controls and instrumentation services, for the detailed design phase of the project. They also fulfilled the principal designer, safety study chair and BIM manager roles, delivering the project to BIM Level 2 and managing the common data environment.

The company have a long history of working with AstraZeneca, including having been involved in a number of earlier facilities for the manufacture of Zoladex. The design of the new facility was based on these pre-existing facilities but incorporated a range of improvements and new technological developments, including integrating a new filling and assembly line within the manufacturing facility and an enhanced fire resistant elevation.

Aerial view of an industrial facility, surrounding roads, and adjacent structures.

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